Development of a System Suitability Test for Two-Dimensional Liquid Chromatography.

Verifying system performance is important when using chromatographic instrumentation for analyzing both known and unknown samples. Typically, system suitability tests (SSTs) are used to verify performance, which involves running an established method and comparing the results to pre-established acceptance criteria. As two-dimensional liquid chromatography (2D-LC) becomes used more widely and in regulated laboratory environments, development and implementation of SSTs will be critical for successful routine use of the 2D-LC technique. [ABSTRACT FROM AUTHOR]