血清嗜酸性粒细胞表达水平与鼻腔鼻窦内翻性乳头状瘤病理 的相关性分析.

Objective: To investigate the correlation between serum eosinophil (EOS) expression level and pathology of inverted papilloma in nasal cavity and sinuses (SNIP). Methods: 63 cases of patients with SNIP admitted to our hospital from January 2016 to January 2020 were selected as the research objects. According to the EOS level of all patients, they were divided into low EOS group, medium EOS group and high EOS group. The clinicopathological characteristics of the three groups were compared, and the correlation between EOS expression level and SNIP pathology was analyzed. After surgical treatment, 63 patients were divided into poor prognosis group and good prognosis group. The clinical related indexes of the two groups were compared, and the prognostic value of EOS expression level in SNIP was analyzed. Results: There was significant difference in clinical stage and pathological diagnosis among the three groups (P<0.05); According to the expression level of EOS, there were more than 300 eosinophils at high level/μL. Medium level: 100-300/μL. Low level:<100/μL. Spearman correlation analysis showed that there was no significant correlation between the expression level of the gender, age, lesion location and EOS (P>0.05), but negative correlation between the expression level of the clinical stage and pathological diagnosis and EOS (P<0.05); There was no significant difference in PLT between the two groups (P>0.05). The levels of L and EOS in the two groups were significantly higher than those in the poor prognosis group, and the levels of N, PLR and NLR in the two groups were lower than those in the poor prognosis group (P<0.05); Logistic regression analysis showed that NLR and EOS were independent prognostic factors of SNIP (P<0.05). Conclusion: The clinical stage and SNIP are negatively correlated with the expression level of EOS, and the application of NLR and EOS can predict the recurrence of SNIP. Therefore, the expression level of EOS can be considered to determine the diagnosis and treatment effect of SNIP. [ABSTRACT FROM AUTHOR]