等速肌力训练联合时空针灸灵龟八法治疗老年肝肾亏虚型膝骨关节炎 的疗效及对血清细胞因子的影响.

To observe the curative effect situation and the changes of serum cytokines in elderly patients with liver and kidney deficiency knee osteoarthritis (KOA) after time-space acupuncture Linggui eight methods combined with isokinetic muscle strength training. The clinical study cases were 100 elderly patients with liver and kidney deficiency KOA who were treated in the geriatric medicine department of our hospital from July 2019 to July 2021. According to the random number table method, the patients were divided into study group (50 cases, basic treatment and isokinetic muscle strength training combined with time-space acupuncture Linggui eight methods) and control group (50 cases, basic treatment and isokinetic muscle strength training). The clinical efficacy of traditional Chinese medicine, traditional Chinese medicine symptom score, visual pain simulation (VAS) score, McMaster University Osteoarthritis Index Scale (WOMAC), Lysholm knee score, knee extensor, flexor peak torque (PT), total work (TW), serum interleukin-18 (IL-18), interleukin-6 (IL-6) and tumor necrosis factor-琢 (TNF-琢) levels were compared between the two groups. The total clinical effective rate of the study group was significantly higher than that of the control group (P<0.05). After treatment, the Lysholm knee score of the study group was higher than that of the control group, while traditional Chinese medicine symptom, WOMAC and VAS scores were lower than those of the control group (P<0.05). After treatment, IL-6, TNF-琢 and IL-18 of the study group were lower than those of the control group (P<0.05). The PT and TW of knee extensor and flexor of the study group were higher than those of the control group (P<0.05). Isokinetic muscle strength training combined with time-space acupuncture Linggui eight methods in the treatment of elderly patients with liver and kidney deficiency KOA has a significant effect, which can improve clinical symptoms, promote the recovery of knee joint function, and effectively reduce the levels of serum IL-6, IL-18 and TNF-琢, which has certain clinical application value. [ABSTRACT FROM AUTHOR]