Brønsted acid-promoted three-component reaction of 2-methoxythiophene, sulfinates and water: Synthesis of γ-mercapto-β-sulfonyl esters.

Authors :: Chen, Xianlie
Luo, Yixin
Zeng, Qingle
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Jun2022, Vol. 100, pN.PAG-N.PAG. 1p.
Publication Year :: 2022
Abstract: [Display omitted] A facile Brønsted acid-promoted three-component reaction of 2-methoxythiophene, sulfinates and water at room temperature has been discovered. Under the mild conditions, a series of γ- mercapto -β- sulfonyl esters were obtained in moderate to good yields. The control experiments support the reaction mechanism involves in three processes: 1,5-H shift, Michael addition and ring opening in water. [ABSTRACT FROM AUTHOR]

Language :: English
ISSN :: 00404039
Volume :: 100
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 157385917
Full Text :: https://doi.org/10.1016/j.tetlet.2022.153884

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