Neurotrophin-3 Enhances the Effectiveness of Cell Therapy in Chronic Spinal Cord Injuries.

Authors :: Stepanova, O. V.
Voronova, A. D.
Chadin, A. V.
Fursa, G. A.
Karsuntseva, E. K.
Valikhov, M. P.
Semkina, A. S.
Reshetov, I. V.
Chekhonin, V. P.
Source :: Bulletin of Experimental Biology & Medicine. May2022, Vol. 173 Issue 1, p114-118. 5p.
Publication Year :: 2022
Abstract: Neurotrophin-3 enhances the effectiveness of human olfactory ensheathing cells in improving hind limb mobility in rats with post-traumatic cysts of the spinal cord. Transplantation of olfactory ensheathing cells into spinal cord cysts reduced their size; neurotrophin-3 did not modulate this effect. Combined preparation of human olfactory ensheathing cells and neurotrophin- 3 can be used in neurosurgery for the treatment of patients with spinal cord injuries. [ABSTRACT FROM AUTHOR]

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