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Is the‘Accelerator Hypothesis’ worthy of our attention?
- Source :
-
Diabetic Medicine . Feb2005, Vol. 22 Issue 2, p115-117. 3p. - Publication Year :
- 2005
-
Abstract
- The article discusses the accelerator hypothesis, which postulated that diabetes is, in fact, a single disease, rather than two distinct entities. The hypothesis argued that the two types of diabetes are distinguished only by the rate of beta-cell loss, and the specific accelerator(s)' responsible. It postulated that there are three accelerators. The first accelerator is the intrinsic potential for a high rate of beta-cell apoptosis, a necessary but insufficient step in the development of diabetes. In other words, the absence of this potential protects against the development of diabetes and vice versa.
Details
- Language :
- English
- ISSN :
- 07423071
- Volume :
- 22
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Diabetic Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 15722757
- Full Text :
- https://doi.org/10.1111/j.1464-5491.2005.01532.x