Visual Analysis of Literature about Curcumin and Diabetes Based on Web of Science.

[Objectives] To analyze the current research situation, hotspots and trends of curcumin and diabetes in recent 10 years. [Methods] Web of Science database was set as data source, the annual number of papers, the distribution of authors, the distribution of country/institution, the distribution of journals, the distribution of key words in the literature about curcumin and diabetes from January 1,2010 to March 31, 2021 were quantitatively and visually analyzed with the aid of visualization software Bibliometrix. [Results] A total of 475 articles were included, and the annual number of papers was on the rise; the top three high-yielding countries were China (120 papers), India (65 papers), and the United States (58 papers). In terms of international cooperation, China and the United States had the most cooperation (27 papers); the top three high-yielding institutions were Wenzhou Medical University (42 papers), Mashhad University of Medical Sciences (41 papers) and Tehran University of Medical Sciences (30 papers); the most frequently cited authors were Wang Y (19 times), Li X (13 times), Li Y (12 times), Liang G (12 times) and Zhang Y (12 times); the top three journals in number of papers were Diabetology & Metabolic Syndrome (8 papers), PLoS One (8 papers), and European Journal of Pharmacology (7 papers), and the h index was 7,8, and 6, respectively; the most frequently cited journals were Diabetes (496 times), Journal of Biological Chemistry (486 times), PLoS One (347 times), Diabetes Care (284 times), and European Journal of Pharmacology (229 times); the most frequent key words mainly included oxidative stress, curcumin, insulin-resistance and expression; the hotspots were insulin resistance and NF-kP>, mainly focusing on in vitro experiments. [Conclusions] The curcumin has good therapeutic potential in improving insulin resistance, inhibiting inflammation and oxidative stress, etc. The results are expected provide a reference and basis for scientific researchers to understand the current situation of curcumin and diabetes research and cany' out the further research. [ABSTRACT FROM AUTHOR]