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Evaluation of layered application of superoxide solution during closure for preventing surgical wound infection-A study of 100 cases.
Evaluation of layered application of superoxide solution during closure for preventing surgical wound infection-A study of 100 cases.
- Source :
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Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research) . 2021, Vol. 12 Issue 6, p960-970. 11p. - Publication Year :
- 2021
-
Abstract
- Background: This study was contemplated with the view to evaluate the layered application of superoxide solution during closure of surgical wounds to assess its role in preventing or containing wound infection in contaminated cases. Methods: All the patients admitted to the surgery wards at Guru Nanak Dev Hospital, attached to Govt. Medical College, Amritsar, who had undergone any sort of surgical intervention due to inflammatory pathology of any organ or perforation of hollow viscus or contaminated peritoneal cavity were taken. This is a comparative study of 100 cases in which two groups were taken: The study group comprised of 50 cases including cases of inflammatory pathology of any organ as well as all cases of emergency laparotomies on which thehypochlorous acid solution was used in each layer during closure of the wound after achieving complete hemostasis. The control group which comprised of 50 cases of inflammatory pathology of any visceral organ as well as all cases of emergency laparotomies in which the closure of the wound was done after achieving complete hemostasis using conventional methods of closure. Final outcome was evaluated on the basis of clinical, operative, radiological findings. The study was conducted after approval from Institutional Ethics Committee, Government Medical College, Amritsar. Written informed consent of all the patients was to be obtained. Results:We found that SSI was higher in the control group compared to the study group. There was significant difference in the incidence of post operative fever in the two groups, with post operative fever present in 20 patients from the control group and only 6 cases from the study group. Skin dehiscence was present in 7 cases in the study group and 15 cases of the control. Sheath dehiscence was present in 8 cases of the study group and 19 cases of the control group. Burst abdomen was present in 2 cases in the study group compared with 8 cases of the control. With these results, this study shows that super-oxidized solution is effective and safe in reducing post-operative complications such as SSI and burst abdomen. It also significantly reduces post-operative morbidity and facilitatesearly recovery. The incidence of delayed complications such as hypertrophic scar and seroma formation were also lower in the study group. The duration of hospital stay was also less in the study group as compared to the control group, with 44% patients being discharged within a week in the study group as compared to just 14 % of the control group. Conclusion:Super-oxidized solution requires no dilution or special handling or disposal. Thus, layered application of super-oxidized solution during closure of wounds could become a useful modality as compared to conventional methods of closure. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09753583
- Volume :
- 12
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research)
- Publication Type :
- Academic Journal
- Accession number :
- 156953844