新型GSH 荧光传感材料的合成与性能研究.

Using Rhodamine B hydrazide as the fluoroph ore, a fluorescent probe with disulfide bond, RNSS, is designed and synthesized, which can specifically recognize in acetonitrile and aqueous solution (v/v = 1 :1) glutathione (GSH). The structure characterization and performance of the probe are analyzed by infrared spectroscopy, nuclear magnetic resonance spectroscopy, and fluorescence spectroscopy. The experimental results show that when GSH is added to the probe solution, under the excitation of 561 nm light, it has obvious pink fluorescence at 585 nm, and other amino acids have no fluorescence response, indicating that it has good specific selectivity and anti--interference ability. At the same time, the detection limit of the probe for GSH is 6.063 X 1 ()_b mol/L, which indicates that it has high sensitivity. The fluorescence spectrum titration curve and Job-plot analysis show that the two are replaced by disulfide bond reaction 1 :1 method to form complexes. [ABSTRACT FROM AUTHOR]