Prevalencia de infección por Treponema pallidum en individuos atendidos en un centro especializado de Medellín, Colombia.

Objective: To describe the prevalence of Treponema pallidum infection in individuals treated in a specialized medical center in Medellín, Colombia in 2019. Methodology: A cross-sectional study was conducted, including 776 subjects of the general population (apparently healthy-asymptomatic and without risk factors for syphilis), 126 men who have sex with men (msm) and 190 vulnerable young people (low socioeconomic strata, unemployed and low educational level) which were identified within and beyond spaces of concentration of msm and nongovernmental organizations. A survey and a detection test for IgG, IgM and IgA for T. pallidum specific antibodies were used as the primary information source. Results: Prevalence of T. pallidum infection was 0.53 % in vulnerable young participants, 2.19% in the general population and 16.67 % in msm. The odds ratio of infection in subjects aged between 51 and 60 years was 13.8 (95% ci = 3.5-51.5) compared to that found in young people aged between 21 and 30 years; 12.0 (95% ci = 1.8-79.2) comparing those with low educational level to university students; 3.3 (95% ci = 1.1-9.9) for people without health insurance compared to those belonging to the contributory health insurance regime; and 8.1 (ci 95 % = 2.8-23.0) in those who have sex with key groups versus those who do not report these practices. Conclusion: A low prevalence of T. pallidum infection was found in young participants, followed by subjects belonging to the general population and was higher in msm. Groups with the highest risk were identified (among the three subgroups studied), including subjects excluded from prevention programs, with a confluence of sexual risk factors and socioeconomic deprivation. [ABSTRACT FROM AUTHOR]