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Diabetic ketoacidosis shortly after COVID‐19 vaccination in a non–small‐cell lung cancer patient receiving combination of PD‐1 and CTLA‐4 inhibitors: A case report.

Authors :
Makiguchi, Tomonori
Fukushima, Takashi
Tanaka, Hisashi
Taima, Kageaki
Takayasu, Shinobu
Tasaka, Sadatomo
Source :
Thoracic Cancer. Apr2022, Vol. 13 Issue 8, p1220-1223. 4p.
Publication Year :
2022

Abstract

We describe a case of diabetic ketoacidosis (DKA) shortly after the SARS‐CoV‐2 (COVID‐19) vaccination in a 65‐year‐old woman with non–small‐cell lung cancer under a combination treatment of programmed cell death protein 1 (PD‐1) and cytotoxic T‐lymphocyte‐associated protein 4 (CTLA‐4) inhibitors. She had no history of diabetic mellitus. A few days after the second shot of COVID‐19 vaccination, she developed DKA. We speculate that the immune‐related adverse event and immunogenicity of vaccination synergistically induced DKA. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
17597706
Volume :
13
Issue :
8
Database :
Academic Search Index
Journal :
Thoracic Cancer
Publication Type :
Academic Journal
Accession number :
156361606
Full Text :
https://doi.org/10.1111/1759-7714.14352