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Synthesis of β- anti -Substituted α-Amino Acids through Iridium-Catalyzed Alkylation/Chelation-Controlled Nucleophilic Addition.
- Source :
-
Synlett . Apr2022, Vol. 33 Issue 7, p655-658. 4p. - Publication Year :
- 2022
-
Abstract
- An Ir/Ag dual-catalysis method has been developed for the synthesis of β- anti -substituted α-amino acids in high yields and with good enantioselectivities through a ligand/chelation-control strategy. By using this chiral-ligand-control strategy, a natural product for the regulation of a plant-growth hormone was synthesized on a gram scale in three steps. [ABSTRACT FROM AUTHOR]
Details
- Language :
- German
- ISSN :
- 09365214
- Volume :
- 33
- Issue :
- 7
- Database :
- Academic Search Index
- Journal :
- Synlett
- Publication Type :
- Academic Journal
- Accession number :
- 156152656
- Full Text :
- https://doi.org/10.1055/s-0040-1719909