Questionnaire‐based approach to sleep‐wake disturbance in patients with chronic liver disease.

Questionnaire-based approach to sleep-wake disturbance in patients with chronic liver disease Keywords: chronic liver disease; dynapenia, hepatic encephalopathy; liver cirrhosis; sarcopenia; sleep-wake disturbance EN chronic liver disease dynapenia, hepatic encephalopathy liver cirrhosis sarcopenia sleep-wake disturbance 327 328 2 04/05/22 20220401 NES 220401 See article in Hepatology Research 52: 364-370. Miyaaki et al. recently reported the prevalence of sleep-wake disturbance in 271 CLD patients (median age: 70 years) and revealed the association between CLD-related complications and sleep disorder.3 In their cohort, 50.2% of patients had sleep disorders, which was much higher than the general Japanese population.4 Importantly, they revealed that CLD-related complications, including muscle cramps, covert HE, and dynapenia, were significantly associated with sleep disorders. [Extracted from the article]