An Enzyme-free Electrochemical H2O2 Sensor Based on a Nickel Metal-organic Framework Nanosheet Array.

In this work, we reported the development of a nickel metal-organic framework nanosheet array on Timesh (Ni-MOF/TM) as an enzyme-free electrochemical sensing platform for H2O2 determination. The as-obtained sensor exhibited outstanding detection properties of H2O2, which might be gifted from the large specific surface area, abundant active sites of Ni-MOF nanoarrays. The sensor displayed a good linear range (0.8 µM-4.6× 10³ µM), a detection limit as low as 0.26 µM, a high sensitivity (307.5 µAmM-1cm-2), and a rapid response. Moreover, this enzyme-free sensor is promising for pointofcare (POC) testing of H2O2 in human serum attribute to the excellent performance of Ni-MOF and the simple preparation process of the sensor. [ABSTRACT FROM AUTHOR]