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Cytotoxic lanostane triterpenoids from the ethanol extract of Schisandra viridis.
- Source :
-
Journal of Asian Natural Products Research . Apr2022, Vol. 24 Issue 4, p321-327. 7p. - Publication Year :
- 2022
-
Abstract
- Three new lanostane triterpenoids, designated as 6-hydroxyl schiglausin A (1), 29-hydroxyl schiglausin D (2), and 6-hydroxyl schiglausin G (3), were isolated from the ethanol extract of the stems of Schisandra viridis. Structural elucidation of all the compounds were performed by spectral methods such as 1D and 2D (1H-1H COSY, HMQC, and HMBC) NMR spectroscopy, in addition to high resolution mass spectrometry. The isolated compounds were tested in vitro for cytotoxic activities. As a result, compound 1 exhibited cytotoxic activities for all six tested human lung cancer cell lines with IC50 values less than 10 μM. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10286020
- Volume :
- 24
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Journal of Asian Natural Products Research
- Publication Type :
- Academic Journal
- Accession number :
- 155893244
- Full Text :
- https://doi.org/10.1080/10286020.2021.1918120