Editorial of Special Issue "Inflammasomes and Inflammation".

Although inflammation is a host-protective mechanism from infection and cellular danger signals, chronic inflammation is a major risk factor for various human diseases [[1], [3]]. The research article by Hytti et al. analyzed the effect of dysfunctional protein clearance on inflammation and inflammasome activation in induced pluripotent stem-cell-derived retinal pigment epithelial (iPSC-RPE) cells generated from an age-related macular degeneration (AMD) patient. 35163466 15 Peladeau C., Sandhu J.K. Aberrant NLRP3 Inflammasome Activation Ignites the Fire of Inflammation in Neuromuscular Diseases. [Extracted from the article]