Dominant Effects of CCR2-CCRS Haplotypes in HIV-1 Disease Progression.

Authors :: Winkler, Cheryl A.
Hendel, Houria
Carrington, Mary
Smith, Michael W.
Nelson, George W.
O'Brien, Stephen J.
Phair, John
Vlahov, David
Jacobson, Lisa P.
Rappaport, Jay
Vasilescu, Alexandre
Bertin-Maghit, Sebastien
Ping An
Wei Lu
Andrieu, Jean-Marie
Schächter, Fran çois
Therwath, Amu
Zagury, Jean-François
Source :: JAIDS: Journal of Acquired Immune Deficiency Syndromes. 12/1/2004, Vol. 37 Issue 4, p1534-1538. 5p. 2 Charts.
Publication Year :: 2004
Abstract: Reports the relative contributions to AIDS progression of three promoter haplotypes of CCR2-CCR5. Comparison of the rapid progression with a seroconverter control group including intermediate progressors to AIDS; Data indicating that factors other than CCR5 or CCR2 genetic variants must be responsible for the long-term maintenance of nonprogression.