The Diagnostic Accuracy of Xpert Xpress to SARS-CoV-2: A systematic review.

• The articles included in the analysis are comprehensive. • The analysis results show that Xpress Xpert has high diagnostic efficiency and short detection time, so we suggest that Xpress Xpert be used as the gold standard for SARS-COV-2 detection • The Xpress Xpert is fast, accurate, and low-cost, so it can be used for large large-scale screening. The SARS-CoV-2 infection rate, as well as mortality rate, is high. There is an urgent need for a high-throughput, accurate and reliable method of diagnosing COVID-19 pneumonia. We included references from databases, such as PubMed, Cochrane Library, Web of Science, and Embase, and extracted data. Then, MetaDisc and STATA were used to establish forest plots and funnel plots for meta-analysis. We collected 14 articles and performed a systematic review. The following results were obtained: sensitivity and specificity were 0.97 (0.96 to 0.98) and 0.97 (0.96 to 0.98) respectively; PLR and NLR were 24.51 (16.63–36.12) and 0.03 (0.01 to 0.10) respectively, DOR was 975.15 (430.11–2210.88), and AUC was 0.9926. When Xpress detects SARS-CoV-2 in different samples, the heterogeneity is small and the specificity and sensitivity are extremely high. We recommend the employment of Xpert Xpress analysis in rapid screening. [ABSTRACT FROM AUTHOR]