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Hybrid odontogenic lesions: A systematic review of 203 cases reported in the literature.
- Source :
-
Journal of Oral Pathology & Medicine . Jan2022, Vol. 51 Issue 1, p5-12. 8p. 2 Color Photographs, 1 Diagram, 3 Charts. - Publication Year :
- 2022
-
Abstract
- Background: Hybrid odontogenic lesions combine histopathological characteristics of two or more odontogenic cysts and/or tumours. The aim of this study was to evaluate the available data on hybrid odontogenic lesions (HOL) and to analyse their epidemiological/clinical features and biological behaviour. Methods: An electronic search was done in January 2021 using multiple databases. Eligibility criteria encompassed publications with sufficient clinical and histological information to confirm the tumours' diagnoses. Results: A total of 147 articles were included in this study, comprising 203 cases. Calcifying odontogenic cyst associated with odontoma (COC/OD) (37/18.2%) was the most common HOL. Females were more affected with a mean age of 24.9 years. Lesions presented as asymptomatic swellings, with a mean evolution time of 8.2 months (0.3–96), and mean tumour size of 4.8 cm (0.3–7). Radiographic aspects frequently showed radiolucent (139/68.4%) and unilocular (52/25.6%) images with well‐defined limits (48/23.6%). The lesions mostly affected mandibular pre‐molars (69/34%) and mandibular molars (69/34%) regions. Enucleation (89/43.8%) and surgical excision (59/29%) were the most common treatment modalities. The mean follow‐up time was 33.8 months (0.5–216 months) and recurrences were observed in four cases (1.9%), all of which were central odontogenic fibroma associated with central giant cell granuloma (COF/CGCG). Conclusion: COC/OD is the most common HOL and recurrence is a rare event, being usually associated with the diagnosis of COF/CGCG. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09042512
- Volume :
- 51
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Journal of Oral Pathology & Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 154795714
- Full Text :
- https://doi.org/10.1111/jop.13238