Dosimetric Consequences of FFF, FF & Photon Beam Energy on VMAT Plan in Prostate Cancer.

Purpose: The research intended to figure out the impact on treatment plan quality & dosimetric certainty of FF & FFF-VMAT plan using Photon beam energy (PBE) of 6MV & 10MV for prostate cancer (PC) along with lymph nodes (LN). Materials & Method: In this retrospective investigation, VMAT plans were created with FFF & FF mode of treatment using the eclipse TPS version 13.5. Each plan subsists two target volume structures: PTVPC comprised the entire prostate cancer& PTVPC + PTVLymph For statistical plan assessment, dosimetric factors were analyzed to measure Nodes. delivery performance. Result:No significant (p>0.05) differences observed for PTVPC & PTVPC+LN coverage in low & high PBE for both FF-VMAT & FFF-VMAT.Low PBE significantly (p<0.05) observed higher numbers of MUs as compared with high PBE, therefore, Lower MUs alleviate the head scattering & leakage radiation & the potential risk of secondary malignancy. A lightly higher low dose volumes were observed for 6MV VMAT plans compared to 10MV VMAT plans. Conclusion: The integral dose was higher in low energy photons (FF-FFF 6MV) when correlated with high energy photons (FF-FFF 10MV) while No significant difference was observed in respect of PTVPC & PTVPC+LN coverage and HI. Significant difference observed in MU value increases in FFF-VMAT. [ABSTRACT FROM AUTHOR]