Analytical performance evaluation of the new sST2 turbidimetric assay implemented in laboratory automation systems.

Keywords: ASPECT-PLUS sST2 assay; automation systems; heart failure; SEQUENT-IA™sST2 assay; Siemens ADVIA CHEMISTRY XPT EN ASPECT-PLUS sST2 assay automation systems heart failure SEQUENT-IA™sST2 assay Siemens ADVIA CHEMISTRY XPT e54 e56 3 01/07/22 20220115 NES 220115 To the Editor, During the last decade, several biomarkers alone or in combination involved in the development of HF have been studied to identify subgroups of patients at high risk of the worst outcome [[1]]. In all 385 patients, median sST2 plasma concentration was 24.98 ng/mL (range, 12.5-250 ng/mL; 25-75th percentiles, 19.43-51.94 ng/mL) measured by the ASPECT-PLUS ST2 assay and 25.11 ng/mL (range, 2.44-314.19 ng/mL; 25-75th percentiles, 18.08-52.78 ng/mL) by the SEQUENT-IA™ ST2 assay. [Extracted from the article]