超声心动图检查指标与胎儿染色体异常的相关性.

To explore the correlation between the indexes of echocardiography and fetal chromosomal abnormalities. A total of 980 high-risk pregnant women, who received prenatal echocardiography in Northwest Women and Children's Hospital from January 2017 to January 2020, were chosen as research subjects, and their echocardiography and chromosomal karyotype detection were carried out, and the specific situation of chromosomal karyotype abnormality was recorded to screen out chromosomal karyotype abnormality Maternal (80 cases) as study group, another 900 cases of normal maternal chromosome as control group. The maternal echocardiography indicators left ventricular Tei index, right ventricular Tei index and neck translucent layer thickness (NT) value differences were compared between the two groups. The correlation of the above echocardiographic indicators were explored by Spearman correlation analysis, and a graph of the diagnostic value of echocardiographic indicators for fetal chromosomal abnormalities was finally drawn. (1) The Tei index of left ventricle, Tei index of right ventricle and NT value of the study group were significantly higher than those of the control group, and the difference between the two groups was statistically significant (P<0.05). (2) Correlation analysis showed that NT value was positively correlated with Tei value of left ventricle and TEI value of right ventricle (r=0.8927). (3) ROC curve showed that the AUC of TEI value in left ventricle, TEI value in right ventricle and NT value in the diagnosis of fetal chromosomal abnormalities were 0.9889, 0.7574 and 0.7959 respectively (P<0.05). There is a significant correlation between echocardiographic indexes and fetal chromosomal abnormalities. Echocardiography can be considered as a screening method for fetal chromosomal abnormalities in the clinical application. [ABSTRACT FROM AUTHOR]