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Antihistamines in children: A dermatological perspective.
- Source :
-
Indian Journal of Paediatric Dermatology . Jan-Mar2022, Vol. 23 Issue 1, p8-23. 16p. - Publication Year :
- 2022
-
Abstract
- Antihistamines are widely used drugs in pediatric population. First-generation antihistamines have been in use since last many years, though adequate data on their efficacy and safety in pediatric population is scarce. In contrast, second-generation antihistamines have been studied extensively in children and have a better safety profile with more receptor selectivity and less adverse effects. Pruritus has a significant impact on the quality of life in children and its management is of paramount importance. This article reviews the first and second-generation antihistamines in the light of recent advances in the understanding of their pharmacological properties and safety profile in children. An extensive literature search was done; all clinical trials, randomized double-blinded or single-blinded controlled trials, open-label studies, retrospective studies, reviews, case series, and case reports focusing on the use of antihistamines in pediatric age groups were screened. The selected articles were retrieved; the final manuscript was prepared, analyzed, and presented in a narrative fashion. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ANTIHISTAMINES
*CHILD patients
*AGE groups
*ITCHING
*CLINICAL trials
Subjects
Details
- Language :
- English
- ISSN :
- 23197250
- Volume :
- 23
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Indian Journal of Paediatric Dermatology
- Publication Type :
- Academic Journal
- Accession number :
- 154482898
- Full Text :
- https://doi.org/10.4103/ijpd.ijpd_124_21