Presence Hallucinations during Locomotion in Patients with Parkinson's Disease.

Keywords: Parkinson's disease psychosis; non-motor symptoms; illusions; sensorimotor processing; procedural activities EN Parkinson's disease psychosis non-motor symptoms illusions sensorimotor processing procedural activities 127 129 3 01/05/22 20220101 NES 220101 The presence hallucination (PH) is the sensation that somebody is nearby when no one is actually there. Affecting up to 60% of patients with Parkinson's disease (PD) and occurring early, PHs are clinically relevant for indicating potential negative clinical outcome.1-3 Recently, we have induced PHs safely in patients with PD by generating sensorimotor conflicts while patients repeatedly actuated a robotic device providing tactile feedback.4 Patients with symptomatic PHs were more sensitive to such sensorimotor stimulation than those without. The two patients were recruited in Switzerland from La Tour Hospital (Geneva) and Geneva University Hospital and were identified in the setting of an ongoing study on hallucinations in PD. [Extracted from the article]