生肌玉红膏联合康复新液治疗乳腺癌根治术后皮瓣坏死创面不愈的临床效果.

Objective: To investigate the effect of Shengjiyuhong ointment combined with Kangfuxin liquid in treating non-healing wounds of skin flap necrosis after radical mastectomy. Methods: Selected 80 cases of patients with non-healing wounds of skin flap necrosis after radical mastectomy from January 2016 to December 2020, divided into two groups randomly. The control group was treated with Kangfuxin liquid alone, and the observation group was treated with Shengjiyuhong ointment. Compared with the wound surface improvement time of the two groups, the serum tumor necrosis factor-α(TNF-α), interleukin-6 (IL-6), vascular endothelial growth factor (VEGF) and interleukin-8 (IL-8) levels were detected and recorded The wound area and VAS pain score of the two groups. Results: The time of carrion shedding, the appearance of new epithelium, the time of draining the drainage tube, the time of wound healing, the time of hospitalization and the time of upper limb rehabilitation activities in the observation group were significantly shorter than those in the control group (P<0.05); After treatment, the levels of serum IL-6, TNF-αand IL-8, wound area and VAS pain score of the two groups were significantly lower than before treatment, while the VEGF level was significantly increased (P<0.05). And the above indicators of the observation group were significantly improved compared with the control group (P<0.05). Conclusion: Shengjiyuhong ointment combined with Kangfuxin liquid has a significant effect on the non-healing of skin flap necrosis wound after radical mastectomy. It can improve the serum inflammatory reaction level of the patient, thereby further reducing the pain of the patient's wound and promoting healing. [ABSTRACT FROM AUTHOR]