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Comparación y concordancia de las ecuaciones más recomendadas de estimación de filtrado glomerular para el diagnóstico de enfermedad renal crónica en una población de Lima, Perú.
- Source :
-
Revista Medica Herediana . jul-set2021, Vol. 32 Issue 3, p162-170. 9p. - Publication Year :
- 2021
-
Abstract
- Objective: To determine the correlation and agreement between the most frequently used formulas estimate the glomerular filtration rate (GFR) and the measured Creatinine Clearance (CrCl), in a Peruvian population. Methods: Study of correlation and agreement in a population with different stages of renal function. 175 patients were included, grouped by CrCl: Group 1: higher than 140, Group 2: between 140 and 90, Group 3: Between 90 and 60, Group 4: less than 60 ml/min/1,73 m² . Height and weight were measured to calculate body mass index (BMI). Obese patients (BMI>29) were excluded. Using a 24-hour urine collection and a serum creatinine sample, creatinine clearance was measured (normalized for 1.73 m² of body surface). Formulas considered for analysis were: Cockroft and Gault, MDRD, CKD-EPI and a Peruvian formula proposed by Vásquez. Correlation was analyzed by Pearson coefficient between studied formulas and the measured CrCl; and its agreement was studied by Bland Altman analysis using the difference between the result obtained by each formula and the measured CrCl. Results: All studied formulas showed an acceptable degree of correlation but CKD-EPI formula had considerable imprecision. The formulas by Vásquez and MDRD showed slightly favorable differences in patients with CrCl<60 ml/min. Conclusion: We recommend the use of any of the studied formulas with exception of CKD-EPI in our population. [ABSTRACT FROM AUTHOR]
- Subjects :
- *GLOMERULAR filtration rate
*BODY mass index
*CREATININE
*DOSAGE forms of drugs
Subjects
Details
- Language :
- Spanish
- ISSN :
- 1018130X
- Volume :
- 32
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Revista Medica Herediana
- Publication Type :
- Academic Journal
- Accession number :
- 154146632
- Full Text :
- https://doi.org/10.20453/rmh.v32i3.4059