Protection of turbot, <em>Scophthalmus maximus</em> (L.), and rainbow trout, <em>Oncorhynchus mykiss</em> (Richardson), against vibriosis using two different vaccines.

The potency of a whole-cell bacterin (WCB) and a toxoid enriched whole-cell vaccine (WCEB) administered intraperitoncally into raibow trout, Oncorhynchus mykiss (Richardson), were compared. The most effective vaccine was further evaluated by bathing turbot, Scophthalmus maximus (L). These vaccienes were composed of three strains of V. anguillarum, of the serotypes 01 and 02. Both vaccines conferred the highest protection against strains of serotype 01 within 4 weeks, with the toxoid enriched vaccine giving the best results (77 RPS). When trout were revaceinated after 7 weeks with this vaccine, good protection was achieved against strains of serotypes 01 and 02. Interestingly, when the WCEB was administered by bath to turbot, acceptable levels of protection against strains of both serotypes were obtained after 4 weeks of immunization. [ABSTRACT FROM AUTHOR]