ОРГАНИЗАЦИЯ БИОБАНКА В НЕЙРОХИРУРГИИ.

Introduction. Biobank is a large-scale biomedical database and an important research resource for conducting scientific, translational, clinical research aimed at developing new treatment methods in modern medicine. Materials and methods. Biological materials (tumour, venous blood) from patients with glial tumours were selected for the study. Biomaterials were processed and cryopreserved in a biobank. Histological, immunohistochemical and molecular genetic studies were performed to establish the diagnosis. All information about the biosamples was recorded in an electronic biobank database. Results: For three years of research (from 2018 to 2021), 777 aliquots from 269 patients were collected in the biobank of the National Centre for Neurosurgery. These are patients mainly with glial tumor lesions of the brain of the III-IV degree of malignancy. All clinical and pathomorphological results of patients are stored in an electronic information system. Conclusion: This biobank will allow us to search for new methods of treatment, improve the quality and increase the life expectancy of neurosurgical patients in the Republic of Kazakhstan. To attract investment from both domestic and foreign investors in the development of scientific research, which together with the above will contribute to the positive development of the country’s economy. The article was prepared within the state order for scientific programme realization under the budget programme 217 «Development of science», subprogram 101 «Programmed target-oriented financing of scientific and/or scientific-technical activity subjects at the expense of the republican budget», subject: BR10965225 «Development of molecular-cytogenetic research programme and creation of biobank of central nervous system tumours». [ABSTRACT FROM AUTHOR]