CHEMICAL AGENTS AS ANTIMICROBIAL FACTORS.

A wide variety of chemicals can be used as antibacterial agents to prevent contamination. Antiseptics and disinfectants are widely used in hospitals and are an essential element in combating and preventing nosocomial infections. A wide variety of active chemicals or biocides are present in these products. Disinfectants and antiseptics affect bacteria in many ways. The widespread use of antiseptics and disinfectants has contributed to the development of microbial resistance, in particular cross-resistance to antibiotics. In medical practice, antimicrobial agents must be selected taking into account the specific microorganisms, pH, solubility, toxicity, organic material present and last but not least the cost. No ideal antimicrobial chemical exists, however the correct choice and proper use of current substances will result in an adequate level of disinfection. This paper aims to review the main antimicrobial chemical agents, the mechanisms by which they act and their importance in clinical practice. [ABSTRACT FROM AUTHOR]