Modified Trabeculectomy Using Ologen® Collagen Matrix with or without A Cyclodestructive Procedure for Canine Glaucoma: A Retrospective Review of 14 Cases.

Trabeculectomy in the dogs has not generally used because of filtering bleb failure due to episcleral fibrosis and subconjunctival scarring for glaucoma. To overcome this filtering bleb failure, we applied a modified trabeculectomy using ologen® Collagen Matrix (CM) with or without a cyclodestructive procedure for dogs with medically uncontrolled glaucoma. This study was performed as retrospective case series. 14 eyes of 12 dogs with medically uncontrolled glaucoma was evaluated from 2015 through 2016. The dogs were divided into three groups: group 1 (six eyes), modified trabeculectomy using ologen® CM (MTO); group 2 (four eyes), MTO with transscleral cyclophotocoagulation (TSCP); and group 3 (four eyes), MTO with endocyclophotocoagulation (ECP). Data pertaining to signalment, pre- and postoperative intraocular pressure (IOP) and visual acuity, preoperative management, detailed surgical procedures, postoperative treatments, follow-up duration, surgical outcomes, and complications were retrospectively reviewed. The outcomes of trabeculectomy and bleb formation were evaluated using ultrasound biomicroscopy (UBM). IOP was successfully stabilized at < 25 mmHg at different time points in 12 of the 14 (85.7%) eyes. Six of nine eyes (66.7%) maintained vision after surgery, and two of five (40.0%) eyes with preoperative vision loss regained vision after surgery. All eyes except two exhibited successful filtering bleb formation without major complications. IOP showed no significant differences among groups (P > 0.05). Modified trabeculectomy using ologen® CM is easy to perform and demonstrates successful outcomes with minimal postoperative complications. This new surgical technique may be an effective alternative procedure for IOP control in canine glaucoma. [ABSTRACT FROM AUTHOR]