Determination of Fenarimol Residues in Loquat by Using QuEChERS Combined with HPLC-MS/MS.

A method based on QuEChERS combined with high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) was established for the determination of fenarimol residues in loquat. The samples were extracted by acetonitrile, purified by N-primary secondary amine (PSA), and determined by high performance liquid chromatography-tandem mass spectrometry. The results showed that: the linearity of fenarimol was good in the concentration range of 0. 5~200 µg · L-1 (r² = 0. 999 4), the limit of detection was 0. 14 µg · kg-1, and the limit of quantitation was 0.5 µg · kg-1. The average recovery rates of fenarimol were respectively 87.0%, 97.4% and 96. 7% at the adding level of 2, 20 and 200 µg · kg-1, with the relative standard deviations (RSD) of 8. 3%, 7. 9% and 4. 3%, respectively. The method was simple, rapid and sensitive, which could meet the requirements of residue detection. [ABSTRACT FROM AUTHOR]