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Antimicrobial Effect of Calcium Hydroxide Combined with Electrolyzed Superoxidized Solution at Neutral pH on Enterococcus faecalis Growth.
- Source :
-
BioMed Research International . 11/9/2021, p1-8. 8p. - Publication Year :
- 2021
-
Abstract
- Objective. To evaluate the effect of the combination of calcium hydroxide (Ca(OH)2) and a novel electrolyzed superoxidized solution at neutral pH, known as OxOral® on Enterococcus faecalis growth in root canals. Methods. Sixty human teeth were used, from which root canals were infected and randomly divided into the following treatment groups: saline solution, saline solution plus Ca(OH)2, OxOral®, and OxOral® plus Ca(OH)2. Results. A permanent reduction in bacterial growth was observed at days 1, 6, 12, and 18 after OxOral® plus Ca(OH)2 treatment from 4.4 ± 0.074 log 10 CFU / mL to 0.0 ± 0.001 log 10 CFU / mL. In addition, alkaline conditions maintenance was observed from application time (pH = 12.2 ± 0.033) to 18 d posttreatment (pH = 12.6 ± 0.083). Conclusion. The combination of OxOral® and Ca(OH)2 provides an alkaline pH and inhibits E. faecalis growth into the root canals. Our study opens the possibility for further research on the use of OxOral® in endodontic therapy. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ANTIMICROBIAL stewardship
*STATISTICS
*HYDROGEN-ion concentration
*ANALYSIS of variance
*HYDROXIDES
*TIME
*ANTI-infective agents
*TOOTH roots
*HEALTH outcome assessment
*ENTEROCOCCUS
*DESCRIPTIVE statistics
*STATISTICAL sampling
*HYPERTONIC saline solutions
*DATA analysis software
*DATA analysis
*PHARMACODYNAMICS
Subjects
Details
- Language :
- English
- ISSN :
- 23146133
- Database :
- Academic Search Index
- Journal :
- BioMed Research International
- Publication Type :
- Academic Journal
- Accession number :
- 153476789
- Full Text :
- https://doi.org/10.1155/2021/6960143