Genome sequencing as a diagnostic test.

Genome sequencing (or whole genome sequencing) is a comprehensive test capable of detecting nearly all DNA variation in a genome. Next-generation sequencing gene panel test: a targeted test focusing on a predefined list of genes that typically detects only exonic sequence-level variants and exon-level deletions or duplications in those genes. Genome sequencing is a comprehensive genetic test that is being integrated into health care systems internationally. For these reasons, genome sequencing will likely eventually supplant exome sequencing, large next-generation sequencing gene panel tests and chromosomal microarray analysis. [Extracted from the article]