Impact of restoring male fertility with transplantation of in vitro propagated spermatogonial stem cells on the health of their offspring throughout life.

Due to its germline character, SSCT is the only adult stem cell-based transplantation therapy that can restore male fertility and may not only affect the recipient, but also the offspring. Dear Editor, Spermatogonial stem cell transplantation (SSCT) is a potential novel fertility treatment for prepubertal cancer patients that require gonadotoxic treatment. The longer-term health outcomes for children born as a result of IVF treatment: Part I-General health outcomes. [Extracted from the article]