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Anticuerpos antifosfatidilserina/protrombina en pacientes con poliarteritis nodosa.
- Source :
-
Reumatología Clínica . Nov2021, Vol. 17 Issue 9, p521-524. 4p. - Publication Year :
- 2021
-
Abstract
- Anti-phosphatidylserine/prothrombin (aPS/PT) antibodies have been described in cutaneous Polyarteritis Nodosa (PAN) in association with specific manifestations. To determine aPS/PT antibodies in patients with PAN and its correlation with clinical manifestations. Cross-sectional comparative study including PAN patients and 20 controls (10 Microscopic Polyangiitis [MPA] and 10 Behçet's disease [BD]). Clinical and demographic variables, treatment, serological markers, prognosis, activity and damage indexes were evaluated. aPS/PT, anti-cardiolipin (aCL), anti-beta 2 glycoprotein 1 (anti-B2GP1) antibodies, and lupus anticoagulant (LA) were determined. Fourteen patients with PAN were included, 11 (79%) women, with disease duration of 207 months, and mostly inactive disease. Only one patient with PAN and one with BD were positive for aPS/PT IgG. LA was the most frequent antibody identified. One patient with MPA and one with BD were positive for aCL IgM; one with MPA for anti-B2GP1 IgG, and one with PAN for anti-B2GP1 IgM. aPS/PT antibodies are not frequent in patients with longstanding inactive PAN. [ABSTRACT FROM AUTHOR]
Details
- Language :
- Spanish
- ISSN :
- 1699258X
- Volume :
- 17
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Reumatología Clínica
- Publication Type :
- Academic Journal
- Accession number :
- 153237827
- Full Text :
- https://doi.org/10.1016/j.reuma.2020.05.010