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The evolving HIV epidemic and its impact on the HIV testing algorithm: Is it time to change the HIV testing algorithm in South Africa?
- Source :
-
Journal of Clinical Virology . Nov2021, Vol. 144, pN.PAG-N.PAG. 1p. - Publication Year :
- 2021
-
Abstract
- • The evolving epidemic of Human Immunodeficiency Virus type 1 in Sub-Saharan Africa and South Africa. • The impact of the epidemic on diagnostic algorithms. • 2019 World Health Organisation's HIV testing guidelines. • Considerations for implementing the new HIV algorithm in South Africa. HIV-1/2 testing is the first step in ensuring HIV-infected individuals are diagnosed and appropriately managed. The impact of suboptimal HIV-1/2 testing algorithms significantly contributes to the increased rates of misdiagnosis of HIV infection. Recently, the World Health Organization (WHO) recommended that high burden countries revise their testing algorithm from a 2 to 3-test testing strategy in the context of an evolving HIV epidemic. Implementation of a new HIV-testing algorithm must be tailor-made within a national framework and must be balanced out with operational feasibility, patient outcomes, and cost-effectiveness. In this review, we provide an overview of the current state of the HIV epidemic and its impact on HIV testing, further we highlight areas of concern in changing from a 2-step to a 3-step test algorithm in the context of South Africa's HIV epidemic and public health program. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ALGORITHMS
*TREATMENT effectiveness
*HIV infections
*HIV
Subjects
Details
- Language :
- English
- ISSN :
- 13866532
- Volume :
- 144
- Database :
- Academic Search Index
- Journal :
- Journal of Clinical Virology
- Publication Type :
- Academic Journal
- Accession number :
- 153203614
- Full Text :
- https://doi.org/10.1016/j.jcv.2021.104990