Back to Search
Start Over
Hypophosphataemia is common in patients with aneurysmal subarachnoid haemorrhage.
- Source :
-
Acta Anaesthesiologica Scandinavica . Nov2021, Vol. 65 Issue 10, p1431-1438. 8p. 1 Diagram, 3 Charts, 2 Graphs. - Publication Year :
- 2021
-
Abstract
- Introduction: Hypophosphataemia is common in critically ill patients, but neither its prevalence nor its association with outcome have been investigated specifically in patients with aneurysmal subarachnoid haemorrhage (aSAH). Methods: Patients with aSAH and at least one phosphate measurement were included from two independent cohorts; an American cohort extracted from two open‐access databases (Medical Information Mart for Intensive Care‐III and eICU Collaborative Research Database v. 2.0) and a Danish cohort consisting of patients with aSAH admitted to Rigshospitalet, Denmark over a 4‐year period. In each cohort, we calculated the prevalence of mild (0.32–0.80 mmol/L) and severe (<0.32 mmol/L) hypophosphataemia and their association with in‐hospital mortality before and after propensity‐score matching. Results: Hypophosphataemia occurred in 72.4% (95% CI: 68.1–76.3) of patients in the American cohort (n = 471) and 54.9% (50.0–59.7) in the Danish cohort (n = 419). However, it was not associated with mortality in neither full (American: Mild, Odds ratio (OR) 0.99 (0.91–1.07), Severe OR 1.20 (0.95–1.51); Danish: Mild, OR 1.01 (0.95–1.08), Severe OR 1.20 (0.95–1.51)) nor propensity‐score matched cohorts (American (n = 168): Mild, OR 1.06 (0.88–1.28), Severe OR 1.46 (0.96–2.12); Danish (n = 44): Mild, OR 1.16 (0.82–1.65), Severe OR 0.45 (0.13–1.55)). Conclusion: In this retrospective study of patients with aSAH, hypophosphataemia was common. [ABSTRACT FROM AUTHOR]
- Subjects :
- *SUBARACHNOID hemorrhage
*HOSPITAL mortality
*ODDS ratio
*CRITICALLY ill
Subjects
Details
- Language :
- English
- ISSN :
- 00015172
- Volume :
- 65
- Issue :
- 10
- Database :
- Academic Search Index
- Journal :
- Acta Anaesthesiologica Scandinavica
- Publication Type :
- Academic Journal
- Accession number :
- 153064316
- Full Text :
- https://doi.org/10.1111/aas.13973