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Comparative study between ketamine-S-dexmedetomidine and ketamine-S-midazolammethadone in the anesthesia of capuchin monkeys (Sapajus apella).
- Source :
-
Ciência Rural . 2022, Vol. 52 Issue 4, p1-9. 9p. - Publication Year :
- 2022
-
Abstract
- Anesthetic protocols have been developed to obtain the most effective and safe association in wildlife. This study compared the anesthetic effects and cardiorespiratory parameters of ketamine-S (+) (10 mg/kg)/dexmedetomidine (0.020 mg/kg) (KD) and ketamine-S (+) (10 mg/kg)/midazolam (0.5 mg/kg)/methadone (1.0 mg/kg) (KMM) in capuchin monkeys (Sapajus apella). Eight capuchin monkeys were randomly assigned to KD (n = 4) or KMM (n = 4) to evaluate induction, immobilization, and recovery scores, heart and respiratory rate parameters, besides systolic, mean, diastolic arterial pressure and arterial blood gas. There was no difference (P = 0.56) in the quality of induction, immobilization, and anesthetic recovery between the protocols. The time for anesthetic induction was 4 ± 1 min in the KD group and 5 ± 1 min in the KMM group, and these values were statistically equal (P = 0.28). The mean immobilization time in the KD and KMM groups were 35 ± 13 and 33 ± 15 min, respectively. Heart rate was lower in animals in the KD group (P < 0.001), while respiratory rate (P = 0.03), and mean blood pressure (P = 0.046) were higher than that of the animals in the KMM group. Respiratory acidosis occurred in the KMM group, with lower pH (7.25±0.047; P = 0.0055) and higher pCO2 (51 ± 6;mmHg; P = 0.008). Both protocols exhibited good induction quality, immobilization, and anesthetic recovery, despite cardiorespiratory and blood gas alterations observed, which warrants monitoring of cardiorespiratory variables during KD or KMM chemical restraint. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01038478
- Volume :
- 52
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Ciência Rural
- Publication Type :
- Academic Journal
- Accession number :
- 152998041
- Full Text :
- https://doi.org/10.1590/0103-8478cr20200823