Electroporación de plasma rico en plaquetas para el rejuvenecimiento facial.

BACKGROUND: The search for alternatives in the application of platelet rich plasma (PRP) that allow achieving the same or better results with less or no adverse event has motivated the use of virtual mesotherapy (electroporation). OBJECTIVE: To assess whether virtual mesotherapy (electroporation) is equal to or more effective and safer than real mesotherapy in the treatment of facial cutaneous photoaging with platelet-rich plasma. MATERIALS AND METHODS: A prospective, randomized, open and controlled pilot study was carried out in 40 patients with facial skin photoaging at the Hospital Hermanos Ameijeiras from March 1st, 2019 to March 30th, 2020. PRP was applied with two different mesotherapeutic interventions, group 1 (control group, intradermal PRP administered with needles) and group 2 (PRP administered with electroporator), and they were compared with each other. RESULTS: There were included 40 patients; 20 in each group. Light and moderate partial response was obtained in 19/20 patients in group 1 and in 17/20 patients in group 2 (p = 0.605). The adverse events found were pain (20/20), inflammation (20/20) and bruising (6/20) in group 1 and none in group 2 (p < 0.001). The degree of satisfaction was good in 12/20 in group 1 and in 20/20 in group 2 (p < 0.05). CONCLUSIONS: PRP application by electroporation was as effective as conventional mesotherapy, without any adverse event and with a higher degree of satisfaction. [ABSTRACT FROM AUTHOR]