Characterization of otologic involvement in patients with X‐Linked Hypophosphatemia.

In this report of otologic characteristics of XLH patients, we found that one in every four patients with XLH presented with hearing loss. Hearing loss and associated variables Patients with hearing loss had a higher prevalence of tinnitus (5 of 6 patients (83%) vs. 5 of 20 patients (25%), I P i = .018) and a phosphate Z-score significantly lower than patients without hearing loss (-4.59 (SD 1.27) vs. -3.55 (SD 0.83), I P i = .025). Patients with hearing loss had higher prevalence of tinnitus and lower serum phosphate compared to patients without hearing loss. Keywords: FGF23; hearing loss; hereditary hypophosphatemic rickets; otorhinolaryngology; X-linked hypophosphatemia EN FGF23 hearing loss hereditary hypophosphatemic rickets otorhinolaryngology X-linked hypophosphatemia 1251 1256 6 10/14/21 20211101 NES 211101 Key points In this report of otological involvement in XLH patients, 23% of them presented hearing loss. [Extracted from the article]