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Yes, MAM!

Authors :
Means, Robert E.
Katz, Samuel G.
Source :
Molecular & Cellular Oncology. 2021, Vol. 8 Issue 4, p1-3. 3p.
Publication Year :
2021

Abstract

Regulation of cell life and death by members of the BCL-2 family of proteins occurs at the mitochondria. Large portions of the mitochondria's outer membrane are found in tight approximation with the endoplasmic reticulum (ER), known as mitochondria-associated membranes (MAMs) or mitochondria-ER contact sites (MERCs). We recently reported that BOK is present within MAMs where it regulates Ca2+ transfer from the ER to the mitochondria, appropriate MAM components and MERC structure, and apoptosis. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
23723556
Volume :
8
Issue :
4
Database :
Academic Search Index
Journal :
Molecular & Cellular Oncology
Publication Type :
Academic Journal
Accession number :
152789004
Full Text :
https://doi.org/10.1080/23723556.2021.1919473