Lactoferrin, a versatile natural antimicrobial glycoprotein that modulates the host's innate immunity.

The article presents Lactoferrin, a versatile natural antimicrobial glycoprotein that modulates the host's innate immunity. Topics discussed include the antimicrobial activity of lactoferrin was the first to be discovered and was assumed to be solely dependent on its iron-chelating ability; and review the current understandings of the antimicrobial effect, interaction with host cells, and innate immune modulation of lactoferrin.