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Synthesis, characterization and antioxidant activity of quercetin derivatives.
- Source :
-
Synthetic Communications . 2021, Vol. 51 Issue 19, p2944-2953. 10p. 3 Black and White Photographs, 1 Diagram, 5 Charts, 2 Graphs. - Publication Year :
- 2021
-
Abstract
- A series of quercetin derivatives were synthesized via Williamson etherification, Steglich esterification or Koenigs–Knorr glycosylation reaction at 3 and 7 position hydroxyl groups selectively. The structures of the synthesized compounds were characterized and identified by IR, 1H NMR, 13C NMR and HR-MS. The antioxidant capacity of synthesized compounds was determined by total antioxidant capacity assay kit with ABTS method (T-AOC Assay Kit). The results revealed that the compounds Qr-5a, Qr-5b, Qr-5c, Qr-5d and Qr-12 manifested significant antioxidant activities comparing to that of the positive control rutin (TEAC = 3.28), among which the antioxidant capacity of Qr-12 was the strongest, and the TEAC value was 5.19. [ABSTRACT FROM AUTHOR]
- Subjects :
- *OXIDANT status
*CHEMICAL synthesis
*HYDROXYL group
*ETHERIFICATION
*ESTERIFICATION
Subjects
Details
- Language :
- English
- ISSN :
- 00397911
- Volume :
- 51
- Issue :
- 19
- Database :
- Academic Search Index
- Journal :
- Synthetic Communications
- Publication Type :
- Academic Journal
- Accession number :
- 152758867
- Full Text :
- https://doi.org/10.1080/00397911.2021.1942059