Comments on Miceli Sopo et al.

Keywords: food protein-induced enterocolitis syndrome; international consensus guidelines; ondansetron; oral food challenge; pediatrics EN food protein-induced enterocolitis syndrome international consensus guidelines ondansetron oral food challenge pediatrics 1588 1589 2 10/04/21 20211001 NES 211001 To the Editor, We read with great interest the paper Miceli Sopo et al,1 published. The authors described their experience with performing an oral food challenge (OFC) for acute food protein-induced enterocolitis syndrome (FPIES), with a single dose in a full serving size for the age of the culprit food, followed by a 4-h observation period. In terms of severity of reaction, the ondansetron was administered in 1/2 (50%) versus 12/22 (54%) of mild reactions, 4/6 (66.7%) versus 8/22 (36%) of moderate reactions, and 9/9 (100%) versus 3/4 (75%) of severe reactions in our and Miceli Sopo et al, studies, respectively. [Extracted from the article]