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Long-Term Utility of Follicular Unit Excision in Lichen Planopilaris--Correlation of Graft Survival With Histopathological and Ultrasound Biomicroscopic Parameters.

Authors :
Daruwalla, Sanober Burzin
Dhurat, Rachita
Ghate, Smita
Bhatt, Kalpana
Source :
Dermatologic Surgery. Sep2021, Vol. 47 Issue 9, p1243-1248. 6p.
Publication Year :
2021

Abstract

BACKGROUND Hair transplantation in scarring alopecia is challenging and transplant surgeons are hesitant due to fear of poor graft survival apart from the risk of reactivating the disease. OBJECTIVE Survival rate of hair follicles transplanted in cases of lichen planopilaris (LPP). To correlate histopathological and ultrasonography findings and their impact on graft survival. METHODS In 32 patients of inactive LPP included, a 5-cm² recipient area was tattooed. The follicular unit density of the transplanted area was 20 to 25 FU/cm2. Postoperative follow-up was conducted at 6, 12, and 24 months. The recipient area density and ultrasound biomicroscopic parameters were assessed at each follow-up visit. RESULTS The survival of grafts was 78.62% at 12 months, and 79.96% at 24 months. Histopathology variables studied at the time of transplantation such as epidermal atrophy, fibrosis, and inflammatory infiltrate were not found to have any effect on the graft survival. Ultrasonography parameters of the involved scalp skin were found to be markedly improved on follow-up. This suggests that the overall health of the scalp improved after hair transplantation. CONCLUSION Follicular unit excision is a ray of hope for cases of primary cicatricial alopecia such as LPP because the result is satisfying to both the patient as well as the doctor. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10760512
Volume :
47
Issue :
9
Database :
Academic Search Index
Journal :
Dermatologic Surgery
Publication Type :
Academic Journal
Accession number :
152735107
Full Text :
https://doi.org/10.1097/DSS.0000000000003103