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Applications of CRISPR-Cas9 as an Advanced Genome Editing System in Life Sciences.

Authors :
Tavakoli, Kamand
Pour-Aboughadareh, Alireza
Kianersi, Farzad
Poczai, Peter
Etminan, Alireza
Shooshtari, Lia
Source :
BioTech. Sep2021, Vol. 10 Issue 3, p1-17. 17p.
Publication Year :
2021

Abstract

Targeted nucleases are powerful genomic tools to precisely change the target genome of living cells, controlling functional genes with high exactness. The clustered regularly interspaced short palindromic repeats associated protein 9 (CRISPR-Cas9) genome editing system has been identified as one of the most useful biological tools in genetic engineering that is taken from adaptive immune strategies for bacteria. In recent years, this system has made significant progress and it has been widely used in genome editing to create gene knock-ins, knock-outs, and point mutations. This paper summarizes the application of this system in various biological sciences, including medicine, plant science, and animal breeding. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
26736284
Volume :
10
Issue :
3
Database :
Academic Search Index
Journal :
BioTech
Publication Type :
Academic Journal
Accession number :
152733553
Full Text :
https://doi.org/10.3390/biotech10030014