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Efficacy of medical dissolution for suspected struvite cystoliths in dogs.
- Source :
-
Journal of Veterinary Internal Medicine . Sep2021, Vol. 35 Issue 5, p2287-2295. 9p. - Publication Year :
- 2021
-
Abstract
- Background: Medical dissolution of struvite uroliths in dogs is commonly recommended, but data on success rates and complications are limited. Objectives: To evaluate the efficacy of medical dissolution for suspected struvite cystoliths in dogs. Animals: Fifty client‐owned dogs fed a therapeutic dissolution diet, with or without administration of antimicrobials, for treatment of suspected struvite cystoliths. Methods: Single institution, retrospective case series. Medical records were reviewed for dogs with at least 1 follow‐up visit. Dissolution success, complications, and possible predictors of success were evaluated. Results: Full dissolution of cystoliths was achieved in 58% (29/50) of dogs within a median of 35 days (range, 13‐167). Of 21 dogs without success, 7 each had partial dissolution, no dissolution, or undetermined outcome. Uroliths containing >10% nonstruvite mineral were common in the nonsuccess group (11/16 analyzed). Maximum urolith diameter, number of uroliths, and baseline urine pH did not differ significantly between dogs with and without success. Dissolution was more likely in dogs receiving antimicrobial therapy (OR = 16.3, 95% confidence interval 1.9‐787.4, P =.002). Adverse events occurred in 9 dogs (18%); urethral obstructions were the most common, but 3 of 4 dogs with this complication were obstructed on presentation, before trial initiation. Conclusions and Clinical Importance: Results support a medical dissolution trial for dogs with suspected struvite cystoliths. If no reduction in urolith size or number occurs by 1 month, a nonstruvite composition is likely, and alternative interventions should be considered. Dogs presenting with urethral obstructions should not be considered candidates for medical dissolution. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 08916640
- Volume :
- 35
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Journal of Veterinary Internal Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 152674783
- Full Text :
- https://doi.org/10.1111/jvim.16252