Postmenopozal Kadınlarda Kemik Mineral Dansitometri Değerleri ile Hematolojik Parametrelerin Karşılaştırılması.

Objective: We aimed to evaluate the relationship between hemogram values, neutrophil lymphocyte ratio, platelet lymphocyte ratio and bone mineral densitometry values in postmenopausal women and thus to determine which parameter is in a stronger relationship with bone mineral densitometry values. Method: In this study, bone mineral densitometry values, neutrophil lymphocyte ratio, platelet lymphocyte ratio and hematological parameters (white blood cell, red blood cell, hemoglobin, platelet, lymphocyte, monocyte, basophil, neutrophil, eosinophil) of 64 postmenopausal female patients aged 50-60, with a body mass index in the range of 25-30 were retrospectively reviewed. Clinical conditions that may affect bone mineral density or hemogram values (acute and chronic infections, oncological, rheumatological and hematological diseases, chronic liver and kidney diseases, hyperparathyroidism, hypothyroidism, hyperthyroidism, vitamin D deficiency, steroid use, and a history of trauma or blood transfusion in the last one year) were excluded from the study. Then, correlation analysis was performed between bone mineral densitometry values and hematological parameters. Results: In our study, a statistically significant negative correlation was found between platelet lymphocyte ratio and femoral neck bone mineral density, femoral neck Z-score and femoral neck T-score (p=0.004, r=-0.353; p=0.005, r=-0.344; p=0.004, r=-0.359, respectively). In addition, a statistically significant positive correlation was found between monocyte values and femoral neck bone mineral density, femoral neck Z-score and femoral neck T-score. (p=0.030, r=0.272; p=0.038, r=0.259; p=0.022, r=0.285, respectively). There was no relationship between neutrophil lymphocyte ratio and bone mineral densitometry parameters. Conclusion: High platelet lymphocyte ratio and low monocyte value can be simple markers that can be used to help predict changes in bone density ratio after menopause. [ABSTRACT FROM AUTHOR]