Extracellular Vesicles: Biology and Potentials in Cancer Therapeutics.

Background Extracellular vesicles (EVs) are particles wrapped in a lipid bilayer membrane and are naturally released from cells. They emphasized that some EVs (such as tumor exosomes) have a tumor-homing tendency, which has led to the use of EV as a drug carrier to effectively provide cancer treatment. Since the role of platelets in cancer development is well known, and PEV is the most abundant EV in the blood, its possible impact on cancer growth has been strongly discussed. EV Isolation and Characterization Many isolation techniques typically discard large EVs in the early stage of sEV or exosome isolation protocols. [Extracted from the article]