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Current diagnostic approaches to detect two important betacoronaviruses: Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
- Source :
-
Pathology - Research & Practice . Sep2021, Vol. 225, pN.PAG-N.PAG. 1p. - Publication Year :
- 2021
-
Abstract
- Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are two common betacoronaviruses, which are still causing transmission among the human population worldwide. The major difference between the two coronaviruses is that MERS-CoV is now causing sporadic transmission worldwide, whereas SARS-CoV-2 is causing a pandemic outbreak globally. Currently, different guidelines and reports have highlighted several diagnostic methods and approaches which could be used to screen and confirm MERS-CoV and SARS-CoV-2 infections. These methods include clinical evaluation, laboratory diagnosis (nucleic acid-based test, protein-based test, or viral culture), and radiological diagnosis. With the presence of these different diagnostic approaches, it could cause a dilemma to the clinicians and diagnostic laboratories in selecting the best diagnostic strategies to confirm MERS-CoV and SARS-CoV-2 infections. Therefore, this review aims to provide an up-to-date comparison of the advantages and limitations of different diagnostic approaches in detecting MERS-CoV and SARS-CoV-2 infections. This review could provide insights for clinicians and scientists in detecting MERS-CoV and SARS-CoV-2 infections to help combat the transmission of these coronaviruses. [ABSTRACT FROM AUTHOR]
- Subjects :
- *COVID-19
*CORONAVIRUSES
*MERS coronavirus
*SARS-CoV-2
*MEDICAL personnel
Subjects
Details
- Language :
- English
- ISSN :
- 03440338
- Volume :
- 225
- Database :
- Academic Search Index
- Journal :
- Pathology - Research & Practice
- Publication Type :
- Academic Journal
- Accession number :
- 152394883
- Full Text :
- https://doi.org/10.1016/j.prp.2021.153565